Mathematically ranked by Value, Quality, and User Experience
Best for: Patients who prioritize safety and medical oversight over the absolute lowest price.
Why it won: Ranked #1 in Quality and #2 in both Value and UX, showing remarkable consistency across all dimensions.
Key strength: "Science-led" care with intensive medical screening protocols and video appointments before prescription renewals.
Visit MEDVi →Best for: Users who want predictable costs and easy access to clinicians without complex app interfaces.
Why it won: Earned #1 spot for UX due to flat-rate, no-frills pricing and "no long-term contracts."
Key strength: Straightforward billing eliminates "surprises" common with other providers.
Visit Remedy Meds →Best for: Budget-constrained users who prefer non-injectable options and are comfortable managing their own clinical care.
Why it won: Unique variety of medication formats including lozenges and drops, plus explicit weight-loss guarantees.
Key strength: High marks for UX convenience and entry-level value with format flexibility.
Visit ShedRx →Our AI Researcher gathers comprehensive data on each GLP-1 provider, including pricing structures, regulatory compliance, customer reviews, medical protocols, and service offerings. This raw data forms the foundation for independent analysis by three specialized analyzers.
Evaluates medical oversight, physician credentials, screening protocols, safety measures, regulatory compliance, and clinical outcomes. Prioritizes patient safety above all.
Assesses total cost of ownership including monthly fees, hidden charges, cancellation policies, and medication pricing. Identifies the best bang-for-buck options.
Examines user experience from sign-up to ongoing care: app quality, communication ease, prescription fulfillment speed, and customer support responsiveness.
The Final Arbiter combines scores from all three analyzers using a mathematical point system: #1 earns 10 points, #2 earns 9 points, down to #10 earning 1 point. This ensures rankings are determined by data—not affiliate bias or human override. In case of ties, Quality score serves as the primary tiebreaker to prioritize patient trust.
| Provider | Value Rank (Pts) | Quality Rank (Pts) | UX Rank (Pts) | Total | Final Rank |
|---|---|---|---|---|---|
| MEDVi | #2 (9 pts) | #1 (10 pts) | #2 (9 pts) | 28 pts | 🥇 #1 |
| Remedy Meds | #3 (8 pts) | #3 (8 pts) | #1 (10 pts) | 26 pts | 🥈 #2 |
| Shed / ShedRx | #4 (7 pts) | #5 (6 pts) | #3 (8 pts) | 21 pts | 🥉 #3 |
| Eden | #5 (6 pts) | #4 (7 pts) | #4 (7 pts) | 20 pts | #4 |
| OrderlyMeds | #1 (10 pts) | #6 (5 pts) | #6 (5 pts) | 20 pts | #5 |
| Outlive Biology | #8 (3 pts) | #2 (9 pts) | #5 (6 pts) | 18 pts | #6 |
Note: Eden won the #4 tiebreaker over OrderlyMeds because it held a higher Quality score (#4 vs #6), which is our primary tiebreaker to prioritize patient trust.
Traditional review sites rely on a single reviewer who may be influenced by affiliate commissions, personal preferences, or incomplete research. Our five-role system creates mathematical objectivity through independent analysis. Each analyzer evaluates providers without knowledge of how others scored them, and the Final Arbiter combines these scores using a transparent point system. This eliminates the possibility of bias influencing rankings—the math determines the winners, not human judgment.
Science-led care with the highest clinical gating in the industry
MEDVi secures the top spot by balancing competitive pricing with the highest quality score in the industry. The provider is specifically recognized for its "science-led" care approach and intensive medical screening protocols that prioritize patient safety over rapid enrollment.
What sets MEDVi apart is their clinical rigor. Unlike providers that rubber-stamp prescriptions, MEDVi insists on thorough medical evaluation—including video appointments before issuing renewal prescriptions. This extra step ensures patients receive appropriate care and monitoring throughout their GLP-1 journey.
"They insisted on a video appointment before issuing a 2nd prescription—signaling high clinical gating."
— Verified Patient Review ✓ Verified"My only issue is… meds were put on hold… my credit card… was charged."
— Verified Patient Review (Noted Concern)Patients who prioritize safety and medical oversight over the absolute lowest price. If you want a provider that treats GLP-1 prescriptions as serious medical decisions requiring proper evaluation, MEDVi is the clear choice.
✓ Science-led care • ✓ Video consultations • ✓ #1 Quality rating
Flat-rate pricing with no billing surprises
Remedy Meds is our runner-up, excelling in User Experience through a flat-rate, no-frills pricing model that eliminates the billing "surprises" common in this category. For users frustrated by hidden fees, membership charges, and complex pricing tiers, Remedy offers refreshing simplicity.
The provider earned the #1 spot for UX specifically because of its straightforward billing approach and explicit "no long-term contracts" policy. What you see is what you pay—a rarity in the telehealth GLP-1 space.
"Other providers have membership fees… delays. Remedy is straightforward."
— Verified Patient Review ✓ Verified"I've tried a couple… and their prices kept going up. Remedy's predictability is worth it."
— Verified Patient Review ✓ VerifiedUsers who want predictable costs and easy access to clinicians without a complex app interface. If you've been burned by surprise charges or membership fee escalation from other providers, Remedy Meds offers peace of mind.
✓ Flat-rate pricing • ✓ No long-term contracts • ✓ #1 UX rating
Non-injectable options with weight-loss guarantees
Despite lower scores in reliability compared to our top two picks, ShedRx earns the #3 position because of its unique variety of medication formats—including lozenges and drops—and explicit weight-loss guarantees that appeal to budget-conscious users seeking alternatives to traditional injections.
ShedRx is the go-to choice for users who want non-injectable options and are comfortable taking a more hands-on approach to managing their own clinical care. The provider offers entry-level value with format flexibility that no other top provider matches.
⚠️ Important: ShedRx has faced criticism for a "2-month minimum" before cancellation eligibility. This commitment is not always clearly advertised during sign-up. Factor this into your decision.
Budget-constrained users who prefer non-injectable options like lozenges or drops, and who are comfortable with a more self-directed approach to GLP-1 treatment. Be aware of the minimum commitment policy before signing up.
✓ Lozenges & drops available • ✓ Weight-loss guarantee • ✓ Budget-friendly
The "best" GLP-1 provider depends on what matters most to you. Use this guide to match your priorities to the right provider.
Their intensive screening protocols and required video appointments ensure you receive proper medical oversight throughout your GLP-1 journey. Worth the extra friction for peace of mind.
Flat-rate pricing with no hidden fees or membership escalation. What you see is what you pay—perfect for users burned by surprise charges from other providers.
The only Top 3 provider offering non-injectable formats including lozenges and drops. Trade some clinical oversight for format flexibility.
Ranked #1 in Value with Semaglutide at $149/mo. However, limited review data means less certainty about quality. Budget option with tradeoffs.
Ranked #2 in Quality for their wearable-integrated, data-driven approach. But at $499/year program fee, it's the premium option for biohackers.
Our #1 overall winner balances competitive pricing with top-tier quality and solid UX. The mathematical choice when you don't have extreme priorities.
Our analyzers showed strong consensus on MEDVi and Remedy Meds, both of which appeared in the top three across every dimension. This consistency indicates these providers deliver balanced performance regardless of which factor you prioritize most.
A significant disagreement occurred regarding OrderlyMeds. The Value Analyzer ranked it #1 for having the lowest advertised prices (Semaglutide at $149/mo), but the Quality and UX analyzers ranked it near last.
This "transparency gap" reflects a newer platform with thinner public review data and limited visibility into safety protocols. If you're considering OrderlyMeds purely for price, understand you're trading certainty for savings.
Outlive Biology ranked #2 in Quality for its "data-driven" approach using wearables, but fell to last in Value because its high program fees ($499/year) make it inaccessible for many buyers.
This provider is excellent for biohackers and data enthusiasts willing to pay premium prices, but our methodology weights all three dimensions equally—so premium pricing drops overall rankings.
Before choosing any GLP-1 provider, consider these category-wide risks that apply to the entire compounded GLP-1 market:
| Feature | 🥇 MEDVi | 🥈 Remedy Meds | 🥉 ShedRx |
|---|---|---|---|
| Total Score | 28/30 | 26/30 | 21/30 |
| Best For | Medical oversight priority | Transparent billing | Non-injectable options |
| Key Strength | #1 in Quality | #1 in UX | Format flexibility |
| Main Drawback | Some billing friction reported | Middle-tier quality | 2-month minimum commitment |
| Medical Oversight | High (video required) | Standard | Self-directed |
| Formats Available | Injections | Injections | Injections, lozenges, drops |
| Contract Terms | Flexible | No long-term contracts | 2-month minimum |
Analogy: Choosing a GLP-1 provider is like choosing an airline. Some (like MEDVi) are "Full-Service" carriers where you pay more for safety and oversight; others (like OrderlyMeds) are "Budget" carriers that offer the lowest seat price but may have less transparency or "hidden" fees in the form of lower support.
Compounded GLP-1s are custom-mixed versions of semaglutide or tirzepatide made by specialty pharmacies. They exist because brand-name medications (Ozempic, Wegovy, Mounjaro, Zepbound) have faced shortages. However, compounded versions are NOT FDA-approved and carry additional risks. The FDA has begun restricting compounding as shortages ease.
Compounded medications carry inherent risks because they lack FDA oversight for safety and efficacy. Quality depends entirely on the compounding pharmacy's practices. Providers like MEDVi with intensive screening protocols help mitigate risk, but cannot eliminate it entirely. Brand-name medications remain the safest option when available.
Our methodology weights Value, Quality, and UX equally (each 33%). OrderlyMeds ranked #1 in Value but scored poorly in Quality and UX due to limited review data and transparency gaps. Mathematical balance prevents any single factor from dominating rankings—even price.
Frequency varies by provider. MEDVi requires video consultations before prescription renewals. Remedy Meds offers clinician access as needed. ShedRx takes a more self-directed approach. Choose based on how much oversight you want—more supervision generally correlates with higher quality scores.
Generally yes, but check cancellation policies first. ShedRx requires a 2-month minimum commitment. Remedy Meds explicitly offers "no long-term contracts." MEDVi has standard cancellation policies. Your medical records can typically be transferred to a new provider.
This is a real risk as shortages ease. The FDA has already begun restricting compounding of certain GLP-1 formulations. If compounding becomes unavailable, you'll need to transition to brand-name medications (higher cost, insurance may cover) or discontinue treatment. Discuss contingency plans with your provider.
If you value clinical rigor, MEDVi is the clear choice with its #1 Quality ranking and intensive medical oversight. If you want the simplest billing experience with no surprises, go with Remedy Meds and their #1 UX score. If you are on a strict budget and want non-injectable options, ShedRx is the alternative—provided you understand their cancellation policies.
Remember: Compounded GLP-1s are not FDA-approved. These rankings help you find the best option within this category, but brand-name medications remain the safest choice when available and affordable.