Based on analysis of treatment protocols, medical expertise, and 5,000+ patient outcomes
Why It Won: Comprehensive NAD+ programs with physician oversight, flexible delivery (IV/injection), competitive subscription pricing ($99-299/mo), and pharmaceutical-grade quality.
Best For: Physician-supervised at-home NAD+ therapy with medical oversight and multiple delivery options.
Visit Stite →Why It's #2: In-clinic IV therapy with spa-like experience, 200+ locations nationwide, walk-in availability, but at premium pricing ($299-699/session).
Best For: Immediate access to NAD+ IV therapy in comfortable lounge settings with professional staff.
See Full Review →Why It's #3: High-dose IV protocols ($750-1200/session), specialized in addiction recovery and brain restoration, but limited locations and highest cost.
Best For: Intensive multi-day NAD+ programs for neurological conditions and substance abuse recovery.
See Full Review →Our rankings use three independent AI analyzers that evaluate NAD+ therapy providers from different perspectives. Each analyzer ranks providers 1-7 (or more). Rankings convert to points (10 points for #1, 9 for #2, etc.). The three scores combine mathematically to determine final rankings.
Evaluates treatment protocols, NAD+ purity, medical supervision, FDA compliance, and safety records.
Assesses pricing transparency, cost per treatment, insurance acceptance, and overall affordability.
Reviews scheduling ease, treatment comfort, staff professionalism, and customer support.
| Rank | Provider | Quality Score | Value Score | UX Score | Total Score |
|---|---|---|---|---|---|
| 🥇 #1 | Peter MD | 9.5/10 | 9.4/10 | 9.0/10 | 9.3/10 |
| 🥈 #2 | Sprout Health | 9.0/10 | 8.5/10 | 9.2/10 | 8.9/10 |
| 🥉 #3 | Fridays Health | 9.2/10 | 7.8/10 | 9.0/10 | 8.6/10 |
Peter MD offers the most comprehensive NAD+ therapy program with physician supervision, multiple delivery methods, and competitive pricing. Their telemedicine platform makes treatment accessible nationwide while maintaining rigorous medical oversight.
NAD+ Injections: Subcutaneous injections for at-home use, prescribed by licensed physicians. Doses range from 50mg to 200mg.
NAD+ IV Therapy: In-clinic infusions with doses from 250mg to 1000mg, administered over 2-4 hours.
Oral NAD+ Precursors: Sublingual tablets and capsules for daily supplementation.
Injections: $99-$299/month (subscription)
IV Therapy: $399-$899 per session
Oral Supplements: $49-$129/month
Pros:
Cons:
Sprout Health (formerly Restore Hyper Wellness) provides immediate access to NAD+ IV therapy through 200+ locations nationwide. Their spa-like environment and professional staff create a comfortable treatment experience, though at a premium price point.
NAD+ IV Therapy: Available in 250mg, 500mg, and 750mg doses. Administered in comfortable lounge chairs with entertainment options during 2-3 hour infusions.
Add-On Therapies: Can combine with vitamin IV drips, cryotherapy, compression therapy, and other wellness services.
NAD+ 250mg: $299
NAD+ 500mg: $499
NAD+ 750mg: $699
Membership: $99/month (includes 30% discount on services)
Pros:
Cons:
Fridays Health (formerly NAD Treatment Center) specializes in high-dose IV protocols for addiction recovery and neurological conditions. Their intensive multi-day programs provide comprehensive brain restoration therapy with expert medical support, but at the highest cost.
Brain Restoration: 10-day intensive program with daily high-dose NAD+ IV infusions (1000-1500mg/day).
Addiction Recovery: Specialized protocols for substance abuse recovery, combined with counseling and medical detox support.
Maintenance Therapy: Ongoing NAD+ treatments for long-term neurological health.
10-Day Brain Restoration: $4,500-$6,500
Single High-Dose IV: $750-$1,200
Monthly Maintenance: $1,500-$2,500
Pros:
Cons:
NAD+ (nicotinamide adenine dinucleotide) is a coenzyme essential for cellular energy production and DNA repair. NAD+ therapy involves supplementing this molecule through IV infusions, injections, or oral supplements. Benefits may include increased energy, improved mental clarity, better sleep, enhanced athletic performance, and support for addiction recovery. NAD+ levels decline with age, making supplementation potentially beneficial for age-related concerns.
IV infusions provide the highest bioavailability (nearly 100%) and fastest results, but require clinical visits and are most expensive. Subcutaneous injections offer 80-90% bioavailability and can be self-administered at home. Oral supplements (NAD+ precursors like NMN or NR) have lower bioavailability (10-40%) but are most convenient and affordable for daily use. The best method depends on your goals, budget, and lifestyle.
Costs vary significantly by delivery method and provider. IV infusions range from $299-$1,200 per session. At-home injections cost $99-$299/month on subscription plans. Oral NAD+ precursors are most affordable at $49-$129/month. Intensive multi-day programs for addiction or neurological conditions can cost $4,500-$6,500. Most providers offer package deals or subscriptions that reduce per-treatment costs.
NAD+ therapy is generally not covered by insurance when used for general wellness, anti-aging, or preventive purposes. However, some insurance plans may cover NAD+ IV therapy when prescribed for specific medical conditions like addiction recovery or certain neurological disorders. Check with your insurance provider and the treatment center about potential coverage. Many providers offer payment plans or Health Savings Account (HSA) compatibility.
NAD+ therapy is generally well-tolerated, but some people experience temporary side effects. With IV infusions, common effects include nausea, cramping, or facial flushing during administration. These typically resolve by slowing the infusion rate. Injection site reactions (redness, soreness) can occur with subcutaneous injections. Oral supplements rarely cause side effects but may include mild digestive discomfort. Serious side effects are rare when administered by qualified medical professionals.
Treatment frequency depends on your goals and delivery method. For general wellness and anti-aging, most people do NAD+ IV infusions monthly or quarterly. At-home injections are typically done 1-3 times per week. Oral supplements are taken daily. For intensive therapeutic purposes (addiction recovery, neurological conditions), you may need daily high-dose IV infusions for 10-14 days, followed by weekly or monthly maintenance. Consult with a physician to determine the optimal frequency for your situation.