Mathematical ranking based on analysis of customer reviews and three independent AI analyzers
$195–$210/month
Highest score for balanced performance across all three dimensions. Industry-leading speed for sign-up and prescription approval with multi-therapy hormone optimization options.
Best for: Users wanting reliable, affordable maintenance therapy
Visit PeterMD →$199/month ($149 first month)
Top spot for Value with transparent, posted pricing. Smoothest "click-to-ship" experience with flexible plans you can pause or cancel anytime.
Best for: Beginners and price-sensitive users
Visit AgelessRx →$25–$149/month + medication
#1 ranked for User Experience with 40+ biomarker blood panel and comprehensive health dashboard. Best-in-class diagnostics for data-driven optimization.
Best for: Data-driven users who want detailed biomarker tracking
Visit Hone Health →Our AI Researcher compiles comprehensive data on each Sermorelin provider, including pricing structures, treatment protocols, customer reviews from multiple platforms (Trustpilot, BBB, Reddit), regulatory compliance, and service offerings. This creates the factual foundation for analysis.
Evaluates medical expertise, compounding pharmacy standards, physician credentials, treatment protocols, and safety measures. Considers regulatory compliance and clinical oversight.
Assesses total cost of treatment including consultations, medications, shipping, and ongoing monitoring. Calculates cost-per-benefit ratio against competitors.
Reviews the complete patient journey: sign-up process, consultation experience, prescription timeline, customer support quality, and platform usability.
Each analyzer independently ranks providers 1-10. Rankings are converted to points (Rank #1 = 10 points, Rank #2 = 9 points, etc.) and summed mathematically. This eliminates bias—the Final Arbiter simply calculates totals. No human preferences influence the final ranking.
| Provider | Value Rank (Pts) | Quality Rank (Pts) | UX Rank (Pts) | TOTAL | FINAL RANK |
|---|---|---|---|---|---|
| PeterMD | #2 (9 pts) | #2 (9 pts) | #2 (9 pts) | 27/30 | 🥇 #1 |
| AgelessRx | #1 (10 pts) | #3 (8 pts) | #3 (8 pts) | 26/30 | 🥈 #2 |
| Hone Health | #3 (8 pts) | #5 (6 pts) | #1 (10 pts) | 24/30 | 🥉 #3 |
| Genesis Lifestyle Medicine | #5 (6 pts) | #6 (5 pts) | #5 (6 pts) | 17/30 | #4 |
| Invigor Medical* | N/A (0 pts) | #4 (7 pts) | #4 (7 pts) | 14/30 | #5 |
*Invigor Medical was not included in all three analyzer rankings and received 0 points for missing data.
Traditional review sites use a single reviewer who may be influenced by affiliate commissions, personal preferences, or brand relationships. Our five-role system creates mathematical separation: the Researcher only gathers facts, the three Analyzers evaluate independently without seeing each other's work, and the Final Arbiter only performs arithmetic. No single role can manipulate the outcome.
Best Overall • Highest Score for Balanced Performance
PeterMD secured the highest overall score because it achieved Rank #2 in all three critical dimensions: Value, Quality, and User Experience. It offers a powerful combination of affordability and reliable service with multi-therapy hormone optimization options.
"The process was straightforward, but I wish the consultation had been more detailed."
— Verified Customer Verified✓ Fast approval • ✓ Multi-therapy options • ✓ US-compounded
Best for Budget and Convenience
AgelessRx earned the top spot in Value analysis with transparent, posted pricing. Positioned as the best overall value for most consumers due to its low commitment risk and the smoothest "click-to-ship" experience in the industry.
"Love AgelessRx! I love getting the prescriptions that I want for a more healthy lifestyle without leaving my home. Everything has been so easy..."
— Verified Customer Verified✓ $149 first month • ✓ Cancel anytime • ✓ Free shipping
Best for Diagnostics and Data-Driven Optimization
Hone Health earned the #1 spot in User Experience analysis with best-in-class diagnostics including a 40+ biomarker blood panel and comprehensive health dashboard. Ideal for optimization-focused users who value detailed tracking.
"Comprehensive test results and tailored prescriptions included."
— Verified Customer Verified"The data visualization of my hormones was eye-opening."
— Verified Customer Verified✓ 40+ biomarkers • ✓ Health dashboard • ✓ Cancel anytime
You want the most affordable option with transparent pricing and low commitment.
You want consistent quality across all dimensions without major tradeoffs.
You want comprehensive diagnostics and detailed biomarker tracking.
You want to start treatment as quickly as possible with minimal friction.
You want Sermorelin alongside TRT, GLP-1, or other hormone therapies.
You're new to Sermorelin and want an easy, low-risk introduction.
While not scoring in the final Top 3 due to missing data points in the Value and UX analyses, Defy Medical ranked #1 in Quality (10 points). It is considered the "Gold Standard" by experts for customized, comprehensive, and safe hormone management based on complex bloodwork.
Patients with complex health profiles who need a true specialist and are willing to pay the high cost barrier (consult fees + labs) for tailored, IGF-1-goal-based dosing.
Defy Medical's premium pricing and extensive consultation process create a higher barrier to entry. While the quality is exceptional, the Value and UX Analyzers couldn't fully evaluate it against more accessible telehealth options.
| Feature | 🥇 PeterMD | 🥈 AgelessRx | 🥉 Hone Health |
|---|---|---|---|
| Monthly Cost | $195–$210 | $199 ($149 first) | $25–$149 + meds |
| Total Score | 27/30 | 26/30 | 24/30 |
| Value Rank | #2 | #1 | #3 |
| Quality Rank | #2 | #3 | #5 |
| UX Rank | #2 | #3 | #1 |
| Consultation | Fast telehealth | Online assessment | Comprehensive + labs |
| Biomarker Testing | Standard | Standard | 40+ biomarkers |
| Multi-Therapy Options | ✓ TRT, GLP-1 | Limited | ✓ Comprehensive |
| Cancel Policy | Flexible | Cancel anytime | Cancel anytime |
| Best For | Overall balance | Beginners/budget | Data-driven users |
Sermorelin is a synthetic peptide that stimulates your pituitary gland to produce more human growth hormone (HGH). Unlike direct HGH injections, Sermorelin works with your body's natural feedback mechanisms, making it a safer alternative for hormone optimization. Benefits may include improved sleep, increased muscle mass, reduced body fat, and enhanced energy levels.
HGH is the actual hormone injected directly, while Sermorelin stimulates your body to produce its own HGH naturally. Sermorelin is generally considered safer because your pituitary gland regulates production—it won't overproduce. Sermorelin is also more affordable and has fewer regulatory restrictions than direct HGH therapy.
Most users report improved sleep quality within 1-2 weeks. Energy improvements typically appear within 2-4 weeks. Body composition changes (muscle gain, fat loss) usually require 2-3 months of consistent use. Maximum benefits are generally seen at 3-6 months of continuous therapy.
Sermorelin is generally well-tolerated when prescribed by a licensed physician. Common side effects include injection site reactions (redness, swelling), headaches, flushing, and dizziness. Serious side effects are rare. All three of our top providers include physician oversight to monitor for any adverse reactions.
Yes, Sermorelin is a prescription medication in the United States. Legitimate telehealth providers like PeterMD, AgelessRx, and Hone Health include physician consultations to determine if Sermorelin is appropriate for you. Avoid any provider selling Sermorelin without a prescription—this is both illegal and dangerous.
Sermorelin is typically not covered by insurance when prescribed for anti-aging or general wellness. Some insurance plans may cover it for specific medical conditions with documented growth hormone deficiency. Most users pay out-of-pocket, which is why we prioritized Value scoring in our analysis. HSA/FSA accounts can often be used for payment.
Our #1 ranked provider offers fast approval and balanced performance across all metrics